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Pharmacokinetics and pharmacodynamics of nab-paclitaxel in patients with solid tumors: Disposition kinetics and pharmacology distinct from solvent-based paclitaxel

The aim of this study was to characterize population pharmacokinetics and the exposure–neutropenia relationship with nanoparticle albumin-bound (nab)-paclitaxel in patients with solid tumors. Plasma and blood concentrations of paclitaxel and neutrophil data were collected from 150 patients with vari...

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Detalles Bibliográficos
Autores principales:	Chen, Nianhang, Li, Yan, Ye, Ying, Palmisano, Maria, Chopra, Rajesh, Zhou, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Pharmacometrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302229/ https://www.ncbi.nlm.nih.gov/pubmed/24719309 http://dx.doi.org/10.1002/jcph.304

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