Analysis of Genome-Wide RNA-Sequencing Data Suggests Age of the CEPH/Utah (CEU) Lymphoblastoid Cell Lines Systematically Biases Gene Expression Profiles

In human, Lymphoblastoid cell lines (LCLs) from the CEPH/CEU (Centre d'Etude du Polymorphisme Humain – Utah) family resource have been extensively used for examining the genetics of gene expression levels. However, we noted that CEU/CEPH cell lines were collected and transformed approximately t...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Tian, Lei, Lu, Dongsheng, Xu, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302305/
https://www.ncbi.nlm.nih.gov/pubmed/25609584
http://dx.doi.org/10.1038/srep07960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302305/
https://www.ncbi.nlm.nih.gov/pubmed/25609584
http://dx.doi.org/10.1038/srep07960

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