N-(1-Pyrenyl) Maleimide Induces Bak Oligomerization and Mitochondrial Dysfunction in Jurkat Cells

N-(1-pyrenyl) maleimide (NPM) is a fluorescent reagent that is frequently used as a derivatization agent for the detection of thio-containing compounds. NPM has been shown to display a great differential cytotoxicity against hematopoietic cancer cells. In this study, the molecular mechanism by which...

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Detalles Bibliográficos
Autores principales: Huang, Pei-Rong, Hung, Shu-Chen, Pao, Chia-Chu, Wang, Tzu-Chien V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302375/
https://www.ncbi.nlm.nih.gov/pubmed/25632401
http://dx.doi.org/10.1155/2015/798489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302375/
https://www.ncbi.nlm.nih.gov/pubmed/25632401
http://dx.doi.org/10.1155/2015/798489

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