Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells

BACKGROUND: Androgens drive the onset and progression of prostate cancer (PCa) via androgen receptor (AR) signalling. The principal treatment for PCa is androgen deprivation therapy, although the majority of patients eventually develop a lethal castrate-resistant form of the disease, where despite l...

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Detalles Bibliográficos
Autores principales: Munkley, Jennifer, Lafferty, Nicholas P, Kalna, Gabriela, Robson, Craig N, Leung, Hing Y, Rajan, Prabhakar, Elliott, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302442/
https://www.ncbi.nlm.nih.gov/pubmed/25592066
http://dx.doi.org/10.1186/s12885-015-1012-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302442/
https://www.ncbi.nlm.nih.gov/pubmed/25592066
http://dx.doi.org/10.1186/s12885-015-1012-8

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