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Double and multiple knockout simulations for genome-scale metabolic network reconstructions
BACKGROUND: Constraint-based modeling of genome-scale metabolic network reconstructions has become a widely used approach in computational biology. Flux coupling analysis is a constraint-based method that analyses the impact of single reaction knockouts on other reactions in the network. RESULTS: We...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302510/ https://www.ncbi.nlm.nih.gov/pubmed/25649004 http://dx.doi.org/10.1186/s13015-014-0028-y |