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Double and multiple knockout simulations for genome-scale metabolic network reconstructions

BACKGROUND: Constraint-based modeling of genome-scale metabolic network reconstructions has become a widely used approach in computational biology. Flux coupling analysis is a constraint-based method that analyses the impact of single reaction knockouts on other reactions in the network. RESULTS: We...

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Detalles Bibliográficos
Autores principales:	Goldstein, Yaron AB, Bockmayr, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302510/ https://www.ncbi.nlm.nih.gov/pubmed/25649004 http://dx.doi.org/10.1186/s13015-014-0028-y

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