Quinolinic acid toxicity on oligodendroglial cells: relevance for multiple sclerosis and therapeutic strategies

The excitotoxin quinolinic acid, a by-product of the kynurenine pathway, is known to be involved in several neurological diseases including multiple sclerosis (MS). Quinolinic acid levels are elevated in experimental autoimmune encephalomyelitis rodents, the widely used animal model of MS. Our group...

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Detalles Bibliográficos
Autores principales: Sundaram, Gayathri, Brew, Bruce J, Jones, Simon P, Adams, Seray, Lim, Chai K, Guillemin, Gilles J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302518/
https://www.ncbi.nlm.nih.gov/pubmed/25498310
http://dx.doi.org/10.1186/s12974-014-0204-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302518/
https://www.ncbi.nlm.nih.gov/pubmed/25498310
http://dx.doi.org/10.1186/s12974-014-0204-5

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