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Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction

BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...

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Detalles Bibliográficos
Autores principales: Sierra-Fonseca, Jorge A, Najera, Omar, Martinez-Jurado, Jessica, Walker, Ellen M, Varela-Ramirez, Armando, Khan, Arshad M, Miranda, Manuel, Lamango, Nazarius S, Roychowdhury, Sukla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302597/
https://www.ncbi.nlm.nih.gov/pubmed/25552352
http://dx.doi.org/10.1186/s12868-014-0132-4