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Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction
BACKGROUND: Assembly and disassembly of microtubules (MTs) is critical for neurite outgrowth and differentiation. Evidence suggests that nerve growth factor (NGF) induces neurite outgrowth from PC12 cells by activating the receptor tyrosine kinase, TrkA. G protein-coupled receptors (GPCRs) as well a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302597/ https://www.ncbi.nlm.nih.gov/pubmed/25552352 http://dx.doi.org/10.1186/s12868-014-0132-4 |