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Extending the time window of mammalian heart regeneration by thymosin beta 4

Recent studies demonstrated that the heart of 1-day-old neonatal mice could regenerate, with Wt1(+) EPDCs migrating into myocardial regions after partial surgical resection, but this capacity was lost by 7 days of age. By treatment with Tβ4 to maintain Wt1 expression and retain the migrating feature...

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Detalles Bibliográficos
Autores principales: Rui, Liu, Yu, Nie, Hong, Lian, Feng, He, Chunyong, Han, Jian, Meng, Zhe, Zheng, Shengshou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302647/
https://www.ncbi.nlm.nih.gov/pubmed/25284727
http://dx.doi.org/10.1111/jcmm.12421