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Both GPER and membrane oestrogen receptor-α activation protect ventricular remodelling in 17β oestradiol-treated ovariectomized infarcted rats

Clinical and experimental studies have established that gender is a factor in the development of ventricular hypertrophy. We investigated whether the attenuated hypertrophic effect of oestradiol was via activation of phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) t...

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Detalles Bibliográficos
Autores principales: Lee, Tsung-Ming, Lin, Shinn-Zong, Chang, Nen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302651/
https://www.ncbi.nlm.nih.gov/pubmed/25256868
http://dx.doi.org/10.1111/jcmm.12430