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Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients

About 70% of human breast cancers express and are dependent for growth on estrogen receptor α (ERα), and therefore are sensitive to antiestrogen therapies. However, progression to an advanced, more aggressive phenotype is associated with acquisition of resistance to antiestrogens and/or invasive pot...

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Detalles Bibliográficos
Autores principales: Karam, Manale, Bièche, Ivan, Legay, Christine, Vacher, Sophie, Auclair, Christian, Ricort, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302658/
https://www.ncbi.nlm.nih.gov/pubmed/25287328
http://dx.doi.org/10.1111/jcmm.12322