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Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4

BACKGROUND: Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the anatomical localization and the reactivity of subtypes of microglia cells. On the...

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Detalles Bibliográficos
Autores principales: Pepe, Giovanna, Calderazzi, Giorgia, De Maglie, Marcella, Villa, Alessandro Maria, Vegeto, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302702/
https://www.ncbi.nlm.nih.gov/pubmed/25551794
http://dx.doi.org/10.1186/s12974-014-0211-6