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Heterogeneous induction of microglia M2a phenotype by central administration of interleukin-4
BACKGROUND: Acquisition of the M1 or M2 phenotypes by microglia has been shown to occur during the development of pathological conditions, with M1 activation being widely involved in neurotoxicity in relation with the anatomical localization and the reactivity of subtypes of microglia cells. On the...
Autores principales: | Pepe, Giovanna, Calderazzi, Giorgia, De Maglie, Marcella, Villa, Alessandro Maria, Vegeto, Elisabetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302702/ https://www.ncbi.nlm.nih.gov/pubmed/25551794 http://dx.doi.org/10.1186/s12974-014-0211-6 |
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