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Intramolecular N-Glycan/Polypeptide Interactions Observed at Multiple N-Glycan Remodeling Steps through [(13)C,(15)N]-N-Acetylglucosamine Labeling of Immunoglobulin G1

[Image: see text] Asparagine-linked (N) glycosylation is a common eukaryotic protein modification that affects protein folding, function, and stability through intramolecular interactions between N-glycan and polypeptide residues. Attempts to characterize the structure–activity relationship of each...

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Detalles Bibliográficos
Autor principal: Barb, Adam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302832/
https://www.ncbi.nlm.nih.gov/pubmed/25551295
http://dx.doi.org/10.1021/bi501380t