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A fat body-derived apical extracellular matrix enzyme is transported to the tracheal lumen and is required for tube morphogenesis in Drosophila

The apical extracellular matrix plays a central role in epithelial tube morphogenesis. In the Drosophila tracheal system, Serpentine (Serp), a secreted chitin deacetylase expressed by the tracheal cells plays a key role in regulating tube length. Here, we show that the fly fat body, which is functio...

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Detalles Bibliográficos
Autores principales: Dong, Bo, Miao, Guangxia, Hayashi, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302886/
https://www.ncbi.nlm.nih.gov/pubmed/25336738
http://dx.doi.org/10.1242/dev.109975