Making designer mutants in model organisms

Recent advances in the targeted modification of complex eukaryotic genomes have unlocked a new era of genome engineering. From the pioneering work using zinc-finger nucleases (ZFNs), to the advent of the versatile and specific TALEN systems, and most recently the highly accessible CRISPR/Cas9 system...

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Detalles Bibliográficos
Autores principales: Peng, Ying, Clark, Karl J., Campbell, Jarryd M., Panetta, Magdalena R., Guo, Yi, Ekker, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302887/
https://www.ncbi.nlm.nih.gov/pubmed/25336735
http://dx.doi.org/10.1242/dev.102186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302887/
https://www.ncbi.nlm.nih.gov/pubmed/25336735
http://dx.doi.org/10.1242/dev.102186

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