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Genome-wide identification of signaling center enhancers in the developing limb

The limb is widely used as a model developmental system and changes to gene expression patterns in its signaling centers, notably the zone of polarizing activity (ZPA) and the apical ectodermal ridge (AER), are known to cause limb malformations and evolutionary differences in limb morphology. Althou...

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Detalles Bibliográficos
Autores principales: VanderMeer, Julia E., Smith, Robin P., Jones, Stacy L., Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302890/
https://www.ncbi.nlm.nih.gov/pubmed/25273087
http://dx.doi.org/10.1242/dev.110965