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Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation mouse embryos that can be propagated in vitro and, when placed into blastocysts, contribute to all tissues of the embryo and integrate into the normal morphogenetic processes, i.e. they are pluripotent. However, a...

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Detalles Bibliográficos
Autores principales: van den Brink, Susanne C., Baillie-Johnson, Peter, Balayo, Tina, Hadjantonakis, Anna-Katerina, Nowotschin, Sonja, Turner, David A., Martinez Arias, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302915/
https://www.ncbi.nlm.nih.gov/pubmed/25371360
http://dx.doi.org/10.1242/dev.113001