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Improved detection of artifactual viral minority variants in high-throughput sequencing data
High-throughput sequencing (HTS) of viral samples provides important information on the presence of viral minority variants. However, detection and accurate quantification is limited by the capacity to distinguish biological from artificial variation. In this study, errors related to the Illumina Hi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302989/ https://www.ncbi.nlm.nih.gov/pubmed/25657642 http://dx.doi.org/10.3389/fmicb.2014.00804 |