Improved detection of artifactual viral minority variants in high-throughput sequencing data

High-throughput sequencing (HTS) of viral samples provides important information on the presence of viral minority variants. However, detection and accurate quantification is limited by the capacity to distinguish biological from artificial variation. In this study, errors related to the Illumina Hi...

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Detalles Bibliográficos
Autores principales: Welkers, Matthijs R. A., Jonges, Marcel, Jeeninga, Rienk E., Koopmans, Marion P. G., de Jong, Menno D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302989/
https://www.ncbi.nlm.nih.gov/pubmed/25657642
http://dx.doi.org/10.3389/fmicb.2014.00804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302989/
https://www.ncbi.nlm.nih.gov/pubmed/25657642
http://dx.doi.org/10.3389/fmicb.2014.00804

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