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The differential activation of intracellular signaling pathways confers the permissiveness of embryonic stem cell derivation from different mouse strains
The requirement of leukemia inhibitory factor (LIF) for the establishment and maintenance of mouse embryonic stem cells (ESCs) depends on the genetic background of the ESC origin. To reveal the molecular basis of the strain-dependent function of LIF, we compared the activation of the intracellular s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302992/ https://www.ncbi.nlm.nih.gov/pubmed/25564647 http://dx.doi.org/10.1242/dev.112375 |