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The differential activation of intracellular signaling pathways confers the permissiveness of embryonic stem cell derivation from different mouse strains

The requirement of leukemia inhibitory factor (LIF) for the establishment and maintenance of mouse embryonic stem cells (ESCs) depends on the genetic background of the ESC origin. To reveal the molecular basis of the strain-dependent function of LIF, we compared the activation of the intracellular s...

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Detalles Bibliográficos
Autores principales:	Ohtsuka, Satoshi, Niwa, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302992/ https://www.ncbi.nlm.nih.gov/pubmed/25564647 http://dx.doi.org/10.1242/dev.112375

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