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A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate

In developing embryos, gene regulatory networks drive cells towards discrete terminal fates, a process called canalization. We studied the behavior of the anterior-posterior segmentation network in Drosophila melanogaster embryos by depleting a key maternal input, bicoid (bcd), and measuring gene ex...

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Detalles Bibliográficos
Autores principales: Staller, Max V., Fowlkes, Charless C., Bragdon, Meghan D. J., Wunderlich, Zeba, Estrada, Javier, DePace, Angela H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302997/
https://www.ncbi.nlm.nih.gov/pubmed/25605785
http://dx.doi.org/10.1242/dev.117796