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Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen–urokinase plasminogen activator receptor system–regulated secretion during breast cancer progression

INTRODUCTION: Interleukin-like epithelial-to-mesenchymal transition inducer (ILEI) is an essential cytokine in tumor progression that is upregulated in several cancers, and its altered subcellular localization is a predictor of poor survival in human breast cancer. However, the regulation of ILEI ac...

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Detalles Bibliográficos
Autores principales: Csiszar, Agnes, Kutay, Betül, Wirth, Silvia, Schmidt, Ulrike, Macho-Maschler, Sabine, Schreiber, Martin, Alacakaptan, Memetcan, Vogel, Georg F, Aumayr, Karin, Huber, Lukas A, Beug, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303039/
https://www.ncbi.nlm.nih.gov/pubmed/25212966
http://dx.doi.org/10.1186/s13058-014-0433-7