Encapsulation of Pt(iv) prodrugs within a Pt(ii) cage for drug delivery

This report presents a novel strategy that facilitates delivery of multiple, specific payloads of Pt(iv) prodrugs using a well-defined supramolecular system. This delivery system comprises a hexanuclear Pt(ii) cage that can host four Pt(iv) prodrug guest molecules. Relying on host–guest interactions...

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Detalles Bibliográficos
Autores principales: Zheng, Yao-Rong, Suntharalingam, Kogularamanan, Johnstone, Timothy C., Lippard, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303084/
https://www.ncbi.nlm.nih.gov/pubmed/25621144
http://dx.doi.org/10.1039/c4sc01892c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303084/
https://www.ncbi.nlm.nih.gov/pubmed/25621144
http://dx.doi.org/10.1039/c4sc01892c

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