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Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential

INTRODUCTION: Triple-negative breast cancer (TNBC) is a subtype of highly malignant breast cancer with poor prognosis. TNBC is not amenable to endocrine therapy and often exhibit resistance to current chemotherapeutic agents, therefore, further understanding of the biological properties of these can...

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Detalles Bibliográficos
Autores principales: Pelicano, Hélène, Zhang, Wan, Liu, Jinyun, Hammoudi, Naima, Dai, Jiale, Xu, Rui-Hua, Pusztai, Lajos, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303115/
https://www.ncbi.nlm.nih.gov/pubmed/25209360
http://dx.doi.org/10.1186/s13058-014-0434-6