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miR-638 mediated regulation of BRCA1affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer

INTRODUCTION: Triple-negative breast cancer (TNBC) represents 15 to 20% of all types of breast cancer; however, it accounts for a large number of metastatic cases and deaths, and there is still no effective treatment. The deregulation of microRNAs (miRNAs) in breast cancer has been widely reported....

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Detalles Bibliográficos
Autores principales: Tan, Xiaohui, Peng, Jin, Fu, Yebo, An, Shejuan, Rezaei, Katayoon, Tabbara, Sana, Teal, Christine B, Man, Yan-gao, Brem, Rachel F, Fu, Sidney W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303116/
https://www.ncbi.nlm.nih.gov/pubmed/25228385
http://dx.doi.org/10.1186/s13058-014-0435-5