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Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers

INTRODUCTION: The DDX21 RNA helicase has been shown to be a nucleolar and nuclear protein involved in ribosome RNA processing and AP-1 transcription. DDX21 is highly expressed in colon cancer, lymphomas, and some breast cancers, but little is known about how DDX21 might promote tumorigenesis. METHOD...

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Detalles Bibliográficos
Autores principales: Zhang, Yandong, Baysac, Kathleen C, Yee, Lian-Fai, Saporita, Anthony J, Weber, Jason D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303128/
https://www.ncbi.nlm.nih.gov/pubmed/25260534
http://dx.doi.org/10.1186/s13058-014-0449-z