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Sensing of Pyrophosphate Metabolites by Vγ9Vδ2 T Cells

The predominant population of γδ T cells in human blood express a T cell receptor (TCR) composed of a Vγ9 (Vγ2 in an alternate nomenclature) and Vδ2 domains. These cells came into the limelight when it was discovered they can respond to certain microbial infections and tumorigenic cells through the...

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Detalles Bibliográficos
Autores principales: Gu, Siyi, Nawrocka, Wioletta, Adams, Erin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303140/
https://www.ncbi.nlm.nih.gov/pubmed/25657647
http://dx.doi.org/10.3389/fimmu.2014.00688