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A randomized, phase II study of the anti-insulin-like growth factor receptor type 1 (IGF-1R) monoclonal antibody robatumumab (SCH 717454) in patients with advanced colorectal cancer

Overexpression of insulin-like growth factor receptor type 1 (IGF-1R) may promote tumor development and progression in some cancer patients. Our objective was to assess tumor uptake of fluorodeoxyglucose by positron-emission tomography in patients with chemotherapy-refractory colorectal cancer treat...

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Detalles Bibliográficos
Autores principales: Lin, Edward H, Lenz, Heinz-Josef, Saleh, Mansoor N, Mackenzie, Mary J, Knost, James A, Pathiraja, Kumudu, Langdon, Ronald B, Yao, Siu-Long, Lu, Brian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303167/
https://www.ncbi.nlm.nih.gov/pubmed/24905030
http://dx.doi.org/10.1002/cam4.263