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Beta Blockade Protection of Bone Marrow Following Injury: A Critical Link between Heart Rate and Immunomodulation

INTRODUCTION: Severe trauma induces a profound elevation of catecholamines that is associated with bone marrow (BM) hematopoietic progenitor cell (HPC) colony growth suppression, excessive BM HPC mobilization, and a persistent anemia. Previously, propranolol (BB) use after injury and shock has been...

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Detalles Bibliográficos
Autores principales: Baranski, Gregg M, Pasupuleti, Latha V, Sifri, Ziad C, Cook, Kristin M, Alzate, Walter D, Rameshwar, Pranela, Livingston, David H, Mohr, Alicia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303182/
https://www.ncbi.nlm.nih.gov/pubmed/25621308
http://dx.doi.org/10.4172/2329-8820.1000124