Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis

INTRODUCTION: Adrenomedullin (AM) is secreted by breast cancer cells and increased by hypoxia. It is a multifunctional peptide that stimulates angiogenesis and proliferation. The peptide is also a potent paracrine stimulator of osteoblasts and bone formation, suggesting a role in skeletal metastases...

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Detalles Bibliográficos
Autores principales: Siclari, Valerie A, Mohammad, Khalid S, Tompkins, Douglas R, Davis, Holly, McKenna, C Ryan, Peng, Xianghong, Wessner, Lisa L, Niewolna, Maria, Guise, Theresa A, Suvannasankha, Attaya, Chirgwin, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303191/
https://www.ncbi.nlm.nih.gov/pubmed/25439669
http://dx.doi.org/10.1186/s13058-014-0458-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303191/
https://www.ncbi.nlm.nih.gov/pubmed/25439669
http://dx.doi.org/10.1186/s13058-014-0458-y

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