Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis

INTRODUCTION: Spot14 (S14), encoded by the THRSP gene, regulates de novo fatty acid synthesis in the liver, adipose, and lactating mammary gland. We recently showed that S14 stimulated fatty acid synthase (FASN) activity in vitro, and increased the synthesis of fatty acids in mammary epithelial cell...

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Detalles Bibliográficos
Autores principales: Wellberg, Elizabeth A, Rudolph, Michael C, Lewis, Andrew S, Padilla-Just, Nuria, Jedlicka, Paul, Anderson, Steven M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303195/
https://www.ncbi.nlm.nih.gov/pubmed/25472762
http://dx.doi.org/10.1186/s13058-014-0481-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303195/
https://www.ncbi.nlm.nih.gov/pubmed/25472762
http://dx.doi.org/10.1186/s13058-014-0481-z

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