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Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays

INTRODUCTION: Aberrant expression of the embryonic stem cell marker Sox2 has been reported in breast cancer (BC). We previously identified two phenotypically distinct BC cell subsets separated based on their differential response to a Sox2 transcription activity reporter, namely the reporter-unrespo...

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Detalles Bibliográficos
Autores principales: Jung, Karen, Wang, Peng, Gupta, Nidhi, Gopal, Keshav, Wu, Fang, Ye, Xiaoxia, Alshareef, Abdulraheem, Bigras, Gilbert, McMullen, Todd P, Abdulkarim, Bassam S, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303205/
https://www.ncbi.nlm.nih.gov/pubmed/25380620
http://dx.doi.org/10.1186/s13058-014-0470-2