The small molecule C-6 is selectively cytotoxic against breast cancer cells and its biological action is characterized by mitochondrial defects and endoplasmic reticulum stress

INTRODUCTION: The establishment of drug resistance following treatment with chemotherapeutics is strongly associated with poor clinical outcome in patients, and drugs that target chemoresistant tumors have the potential to increase patient survival. In an effort to identify biological pathways of ch...

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Detalles Bibliográficos
Autores principales: Vaden, Rachel M, Gligorich, Keith M, Jana, Ranjan, Sigman, Matthew S, Welm, Bryan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303206/
https://www.ncbi.nlm.nih.gov/pubmed/25425314
http://dx.doi.org/10.1186/s13058-014-0472-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303206/
https://www.ncbi.nlm.nih.gov/pubmed/25425314
http://dx.doi.org/10.1186/s13058-014-0472-0

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