Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer

DNA methylation and histone modifications are important epigenetic modifications associated with gene (dys)regulation. The epigenetic modifications are balanced by epigenetic enzymes, so-called writers and erasers, such as DNA (de)methylases and histone (de)acetylases. Aberrant epigenetic alteration...

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Detalles Bibliográficos
Autores principales: Falahi, Fahimeh, van Kruchten, Michel, Martinet, Nadine, Hospers, Geke, Rots, Marianne G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303227/
https://www.ncbi.nlm.nih.gov/pubmed/25410383
http://dx.doi.org/10.1186/s13058-014-0412-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303227/
https://www.ncbi.nlm.nih.gov/pubmed/25410383
http://dx.doi.org/10.1186/s13058-014-0412-z

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