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Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer
DNA methylation and histone modifications are important epigenetic modifications associated with gene (dys)regulation. The epigenetic modifications are balanced by epigenetic enzymes, so-called writers and erasers, such as DNA (de)methylases and histone (de)acetylases. Aberrant epigenetic alteration...
Autores principales: | Falahi, Fahimeh, van Kruchten, Michel, Martinet, Nadine, Hospers, Geke, Rots, Marianne G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303227/ https://www.ncbi.nlm.nih.gov/pubmed/25410383 http://dx.doi.org/10.1186/s13058-014-0412-z |
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