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Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells
INTRODUCTION: Matrix detachment triggers anoikis, a form of apoptosis, in most normal epithelial cells, while acquisition of anoikis resistance is a prime requisite for solid tumor growth. Of note, recent studies have revealed that a small population of normal human mammary epithelial cells (HMECs)...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303232/ https://www.ncbi.nlm.nih.gov/pubmed/25096718 http://dx.doi.org/10.1186/s13058-014-0420-z |