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Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells

INTRODUCTION: Matrix detachment triggers anoikis, a form of apoptosis, in most normal epithelial cells, while acquisition of anoikis resistance is a prime requisite for solid tumor growth. Of note, recent studies have revealed that a small population of normal human mammary epithelial cells (HMECs)...

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Detalles Bibliográficos
Autores principales: Hindupur, Sravanth K, Balaji, Sai A, Saxena, Meera, Pandey, Shubham, Sravan, Gopalkrishnashetty Sreenivasmurthy, Heda, Namrata, Kumar, M Vijaya, Mukherjee, Geetashree, Dey, Devaveena, Rangarajan, Annapoorni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303232/
https://www.ncbi.nlm.nih.gov/pubmed/25096718
http://dx.doi.org/10.1186/s13058-014-0420-z