Emerging Models for the Molecular Basis of Mammalian Circadian Timing

[Image: see text] Mammalian circadian timekeeping arises from a transcription-based feedback loop driven by a set of dedicated clock proteins. At its core, the heterodimeric transcription factor CLOCK:BMAL1 activates expression of Period, Cryptochrome, and Rev-Erb genes, which feed back to repress t...

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Detalles Bibliográficos
Autores principales: Gustafson, Chelsea L., Partch, Carrie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303291/
https://www.ncbi.nlm.nih.gov/pubmed/25303119
http://dx.doi.org/10.1021/bi500731f

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