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Probing the DNA Structural Requirements for Facilitated Diffusion

[Image: see text] DNA glycosylases perform a genome-wide search to locate damaged nucleotides among a great excess of undamaged nucleotides. Many glycosylases are capable of facilitated diffusion, whereby multiple sites along the DNA are sampled during a single binding encounter. Electrostatic inter...

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Detalles Bibliográficos
Autores principales: Hedglin, Mark, Zhang, Yaru, O’Brien, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303293/
https://www.ncbi.nlm.nih.gov/pubmed/25495964
http://dx.doi.org/10.1021/bi5013707