hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells

Retrotransposition of endogenous retroviruses (ERVs) poses a substantial threat to genome stability. Transcriptional silencing of a subset of these parasitic elements in early mouse embryonic and germ cell development is dependent upon the lysine methyltransferase SETDB1, which deposits H3K9 trimeth...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Peter J., Dulberg, Vered, Moon, Kyung-Mee, Foster, Leonard J., Chen, Carol, Karimi, Mohammad M., Lorincz, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303303/
https://www.ncbi.nlm.nih.gov/pubmed/25611934
http://dx.doi.org/10.1371/journal.pgen.1004933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303303/
https://www.ncbi.nlm.nih.gov/pubmed/25611934
http://dx.doi.org/10.1371/journal.pgen.1004933

Ejemplares similares