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hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells

Retrotransposition of endogenous retroviruses (ERVs) poses a substantial threat to genome stability. Transcriptional silencing of a subset of these parasitic elements in early mouse embryonic and germ cell development is dependent upon the lysine methyltransferase SETDB1, which deposits H3K9 trimeth...

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Detalles Bibliográficos
Autores principales:	Thompson, Peter J., Dulberg, Vered, Moon, Kyung-Mee, Foster, Leonard J., Chen, Carol, Karimi, Mohammad M., Lorincz, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303303/ https://www.ncbi.nlm.nih.gov/pubmed/25611934 http://dx.doi.org/10.1371/journal.pgen.1004933

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