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Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal
[Image: see text] The circulating protein transthyretin (TTR) can unfold, oligomerize, and form highly structured amyloid fibrils that are deposited in tissues, causing organ damage and disease. This pathogenic process is caused by a heritable TTR point mutation in cases of familial TTR-related amyl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303310/ https://www.ncbi.nlm.nih.gov/pubmed/25478940 http://dx.doi.org/10.1021/bi5011249 |