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Multivalency in the Inhibition of Oxidative Protein Folding by Arsenic(III) Species
[Image: see text] The renewed use of arsenicals as chemotherapeutics has rekindled interest in the biochemistry of As(III) species. In this work, simple bis- and tris-arsenical derivatives were synthesized with the aim of exploiting the chelate effect in the inhibition of thiol-disulfide oxidoreduct...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303313/ https://www.ncbi.nlm.nih.gov/pubmed/25506675 http://dx.doi.org/10.1021/bi501360e |