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Ketamine’s Antidepressant Efficacy is Extended for at Least Four Weeks in Subjects with a Family History of an Alcohol Use Disorder

BACKGROUND: A single subanesthetic infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and potent antidepressant properties in treatment-resistant major depressive disorder (TRD). As a family history of an alcohol use disorder is a positive predictor of ketamine’s anti...

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Detalles Bibliográficos
Autores principales: Niciu, Mark J., Luckenbaugh, David A., Ionescu, Dawn F., Richards, Erica M., Vande Voort, Jennifer L., Ballard, Elizabeth D., Brutsche, Nancy E., Furey, Maura L., Zarate, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303351/
https://www.ncbi.nlm.nih.gov/pubmed/25539512
http://dx.doi.org/10.1093/ijnp/pyu039