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Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H(2)S-synthesizing pathways

An increase in the H(2)S (hydrogen sulphide, hereafter sulphide) concentration in pulmonary artery smooth muscle cells (PASMCs) has been proposed to mediate hypoxic pulmonary vasoconstriction (HPV). We evaluated this hypothesis in isolated rat intrapulmonary arteries (IPAs) by examining the effects...

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Detalles Bibliográficos
Autores principales: Prieto-Lloret, Jesus, Shaifta, Yasin, Ward, Jeremy P T, Aaronson, Philip I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303384/
https://www.ncbi.nlm.nih.gov/pubmed/25630260
http://dx.doi.org/10.1113/jphysiol.2014.277046