Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives

The inflammasome is a molecular platform formed by activation of an innate immune pattern recognition receptor seed, such as NLRP3. Once activated, NLRP3 recruits the adapter ASC (apoptosis-related speck-like protein containing a caspase recruitment domain), which in turn recruits procaspase-1. Proc...

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Detalles Bibliográficos
Autores principales: Ozaki, Ema, Campbell, Matthew, Doyle, Sarah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303395/
https://www.ncbi.nlm.nih.gov/pubmed/25653548
http://dx.doi.org/10.2147/JIR.S51250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303395/
https://www.ncbi.nlm.nih.gov/pubmed/25653548
http://dx.doi.org/10.2147/JIR.S51250

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