Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation

Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it re...

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Detalles Bibliográficos
Autores principales: Sun, Lili, Nguyen, Anh Tuan, Spitsbergen, Jan M., Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303426/
https://www.ncbi.nlm.nih.gov/pubmed/25612309
http://dx.doi.org/10.1371/journal.pone.0117249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303426/
https://www.ncbi.nlm.nih.gov/pubmed/25612309
http://dx.doi.org/10.1371/journal.pone.0117249

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