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Using Fluorescent Myosin to Directly Visualize Cooperative Activation of Thin Filaments
Contraction of striated muscle is tightly regulated by the release and sequestration of calcium within myocytes. At the molecular level, calcium modulates myosin's access to the thin filament. Once bound, myosin is hypothesized to potentiate the binding of further myosins. Here, we directly ima...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303648/ https://www.ncbi.nlm.nih.gov/pubmed/25429108 http://dx.doi.org/10.1074/jbc.M114.609743 |