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Using Fluorescent Myosin to Directly Visualize Cooperative Activation of Thin Filaments

Contraction of striated muscle is tightly regulated by the release and sequestration of calcium within myocytes. At the molecular level, calcium modulates myosin's access to the thin filament. Once bound, myosin is hypothesized to potentiate the binding of further myosins. Here, we directly ima...

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Detalles Bibliográficos
Autores principales: Desai, Rama, Geeves, Michael A., Kad, Neil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303648/
https://www.ncbi.nlm.nih.gov/pubmed/25429108
http://dx.doi.org/10.1074/jbc.M114.609743