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Evolving insights on how cytosine methylation affects protein–DNA binding

Many anecdotal observations exist of a regulatory effect of DNA methylation on gene expression. However, in general, the underlying mechanisms of this effect are poorly understood. In this review, we summarize what is currently known about how this important, but mysterious, epigenetic mark impacts...

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Detalles Bibliográficos
Autores principales: Dantas Machado, Ana Carolina, Zhou, Tianyin, Rao, Satyanarayan, Goel, Pragya, Rastogi, Chaitanya, Lazarovici, Allan, Bussemaker, Harmen J., Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303714/
https://www.ncbi.nlm.nih.gov/pubmed/25319759
http://dx.doi.org/10.1093/bfgp/elu040