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Evolving insights on how cytosine methylation affects protein–DNA binding
Many anecdotal observations exist of a regulatory effect of DNA methylation on gene expression. However, in general, the underlying mechanisms of this effect are poorly understood. In this review, we summarize what is currently known about how this important, but mysterious, epigenetic mark impacts...
Autores principales: | Dantas Machado, Ana Carolina, Zhou, Tianyin, Rao, Satyanarayan, Goel, Pragya, Rastogi, Chaitanya, Lazarovici, Allan, Bussemaker, Harmen J., Rohs, Remo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303714/ https://www.ncbi.nlm.nih.gov/pubmed/25319759 http://dx.doi.org/10.1093/bfgp/elu040 |
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